iBio 101

iBio 101 To download the movies to your computer, please right click on the title of the movie you wish to see (in gold, below) and then choose "Save Target/Link As."
	Name and Affiliation	Title	Run Time	Description
	Bonnie Bassler Princeton University	Bacterial Communication	10:24 min	Bassler describes how bacteria use chemical signals to talk to each other. This communication allows them to act as a unified group and accomplish tasks they could never accomplish as individual cells.
	Mary Beckerle University of Utah	Cancer Development	7:11 min	Cancer is the result of the derangement of control pathways that usually keep cell growth in check. Beckerle explains how changes in our genes are ultimately responsible for this out-of-control cell growth.
	Mary Beckerle University of Utah	Genetic Variability in Cancer	5:39 min	Many different genes are turned on or off in different types of cancer and in different patients. In some cases, different genes are affected even in the same tumor types. A better genetic understanding of cancer may lead to new strategies for patient care.
	Elizabeth Blackburn University of California, San Francisco	Telomeres	12:30 min	Telomeres are short, G rich DNA repeats that cap the end of each chromosome. Dysfunctional telomeres result in genomic instability. Blackburn explains how functional telomeres prevent modification of chromosome ends and maintain chromosome length.
	Elizabeth Blackburn University of California, San Francisco	Telomerase	6:00 min	Telomerase is a unique cellular reverse transcriptase that has the vital role of maintaining telomeric DNA at the end of chromosomes. Blackburn and colleagues were awarded the 2009 Nobel Prize in Medicine for their work on telomeres and telomerase.
	Carolyn Bertozzi University of California, Berkeley	Human Blood Groups	3:51 min	The discovery that sugars on the surface of human blood cells determine blood groups (A, B, AB, and O), had a huge impact on modern medicine.
	Carolyn Bertozzi University of California, Berkeley	Influenza Virus Infection	12:22 min	Bertozzi gives a brief introduction to the flu virus, including how it infects cells and how drugs such as Relenza or Tamiflu work.
	Carolyn Bertozzi University of California, Berkeley	Inflammatory Diseases	4:34 min	The binding of white blood cells to the walls of blood vessels is often a first step in inflammatory diseases such as arthritis and asthma. The initial attachment is mediated by sugars and sugar binding proteins on the surface of both the blood cells and blood vessels.
	Elaine Fuchs Rockefeller University	Embryonic Stem Cells	7:41min	Fuchs defines embryonic stem cells, outlines how they are obtained experimentally, and explains why scientists are excited about their great potential for regenerative medicine.
	Elaine Fuchs Rockefeller University	Embryonic Stem Cells: Ethical Considerations	6:22 min	In this lecture, Fuchs examines the controversy surrounding the use of embryonic stem cells for research.
	Elaine Fuchs Rockefeller University	Nuclear Transfer Research	10:40 min	The transfer of the nucleus from an adult cell into an enucleated oocyte can generate stem cells that go on to produce healthy mice. While this technology holds promise for regenerative medicine there are still many hurdles to clear.
	Elaine Fuchs Rockefeller University	Adult Stem Cells	20:26 min	Adult stem cells regenerate a specific set of cells such as skin or blood. Fuchs focuses on skin stem cells and the success of using epidermal cells grown in vitro to treat burn patients.
	Richard Losick Harvard University	Spore Formation in Bacteria	3:03min	Losick uses a very nice animation to illustrate the complex series of steps that the bacteria Bacillus subtilis undergoes during spore formation. It is a fascinating example of development and differentiation in a simple organism.
	Susan Lindquist Whitehead Institute	Protein Folding and Prion Disease	13:40 min	Proteins are folded into intricate, complicated shapes (see Steve Mayo’s iBio101) and misfolding often results in disease. Lindquist describes how prions catalyze protein misfolding resulting in diseases such as Mad Cow Disease. She also gives a great explanation of why budding yeast (S. cereviseae) is such a wonderful lab tool.
	Steve Mayo, California Institute of Technology	Protein Structure	2:41 min	Proteins are the key to most cellular processes. Mayo gives examples of some of the complex structures into which different proteins can fold.
	Ira Mellman Genentech	The Immune Response	12:19 min	The immune response is quite amazing in its ability to provide protection against the bacteria, viruses, and toxins that invade our bodies while not harming us. Mellman accompanies his description of the immune response with engaging video and animation.
	Jeremy Nathans Johns Hopkins University	The Vertebrate Eye	10:14 min	Nathans gives an overview of the vertebrate eye starting with the entire visual system and working down to photoreceptor cells, the visual pigment rhodopsin and finally the chromophore retinal.

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