Introduction to Cancer Biology
Part 1: Beckerle explains that cancer is a genetic disease with mutations in different genes responsible for different tumors. These mutations cause many cellular signaling pathways, including those involved in cell adhesion, to go awry. A good lecture for an undergraduate or graduate class in cancer biology.
Part 2: Zyxin and its Role in Tumor Progression Research on the focal adhesion protein,
Cellular Response to Mechanical Stress
Part 3: In this segment, Beckerle explains how cells detect and respond to mechanical stress such as stretching, with changes to focal adhesions and the actin cytoskeleton. A good lecture for graduate students studying focal adhesions or the cytoskeleton.