Research the Literature on your Own

  1. What has been learned about Leishmania survival within the host cell since this seminar was given (April 2007)?

  2. What has been learned about T. cruzi survival within the host cell since this seminar was given (April 2007)?

  3. What other facts have we learned about cell biology because of the study of Trypanosoma and Leishmania species?

  4. What else has been done using LIT1? Have homologues of this protein been found in other intracellular pathogens?

  5. What other types of cellular processes is calcium signaling involved in? Is this a mechanism that is found only in mammals?

  6. What else has been discovered about lysosomal pathways since this seminar was given? Have any other intracellular pathogens been described that also replicate within the lysosomal pathway or the endocytic pathway?


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