|
The Secretory Pathway
Part 1: In this excellent lecture for undergraduates, Schekman explains how using genetics in Saccharomyces cerevisiae (Baker’s yeast) allowed dissection of the secretory pathway in all eukaryotic cells.
Transport Between the ER and Golgi
Part 2: Protein biochemistry provides additional information to explain how secretory vesicles are formed and fuse with other membranes. This lecture focuses on the in vitro reconstitution of transport between the endoplamic reticulum and the Golgi. Appropriate for advanced undergraduates or graduate students.
|

Part 1: In this excellent lecture for undergraduates, Schekman explains how using genetics in Saccharomyces cerevisiae (Baker’s yeast) allowed dissection of the secretory pathway in all eukaryotic cells.
Part 2: Protein biochemistry provides additional information to explain how secretory vesicles are formed and fuse with other membranes. This lecture focuses on the in vitro reconstitution of transport between the endoplamic reticulum and the Golgi. Appropriate for advanced undergraduates or graduate students.
Part 3: An interesting story of the convergence of basic science and medicine; a mutation in the Sec23 protein is identified as the cause of human disease. Suitable for graduate or medical students.