Protein Folding and Prions
Part 1: This lecture is suitable for an undergraduate cell biology course. Lindquist explains why yeast are a good model system for studying protein folding and how results from experiments in yeast can teach us about mammalian prion diseases.

• Lecture notes
• Recommended reading
• Review questions (Answers*)
• Facilitator questions (Answers*)
• Explain/teach these concepts to a friend
• Research the literature on your own
• See Susan Lindquist' Seminar
• PDF of all materials
• Prepared by Randal Halfmann with help from Karen Allendoerfer, and Susan Lindquist

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Prions and Evolution
Part 2: This research lecture is appropriate for graduate students. A potential role for prions in evolution is discussed.

• Review questions (Answers*)
• Facilitator questions (Answers*)
• Explain/teach these concepts to a friend
• Research the literature on your own
• Papers for journal club
• See Susan Lindquist' Seminar
• PDF of all materials
• Prepared by Randal Halfmann with help from Karen Allendoerfer, and Susan Lindquist