Recommended Reading

Kenyon, C., Chang, J., Gensch, E., Rudner, A., and Tabtiang, R. (1993). A C. elegans mutant that lives twice as long as wild type. Nature 366, 461-464.

Riddle D., Blumenthal T., Meyer B., Priess, R. (1997). C. elegans II. Chapter 28: Environmental factors and gene activities that influence life span.

http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=ce2

More advanced basic reading

Tatar, M., Bartke, A., and Antebi, A. (2003). The endocrine regulation of aging by insulin-like signals. Science 299, 1346-1351.

Dillin, A., Crawford, D.K., and Kenyon, C. (2002). Timing requirements for insulin/IGF-1 signaling in C. elegans. Science 298, 830-834.

Murphy, C.T., McCarroll, S.A., Bargmann, C.I., Fraser, A., Kamath, R.S., Ahringer, J., Li, H., and Kenyon, C. (2003). Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424, 277-283.

Kenyon, C. (2005). The plasticity of aging: insights from long-lived mutants. Cell 120, 449-460.

Libina, N., Berman, J.R., and Kenyon, C. (2003). Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell 115, 489-502.

Wolkow, C.A., Kimura, K.D., Lee, M.S., and Ruvkun, G. (2000). Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Science 290, 147-150.(Wolkow et al., 2000).

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